The Early Christian basilica rises in a densely built-up area of the city lying between the hexagonal basin, the transverse channel, Via Portuensis, and Fossa Traiana. Its construction marks the final stage in a gradual process of transformation of pre-existing complexes built starting in the mid-1st century AD. During the 4th century AD, a residential-type building with mosaic and opus sectile floor was erected, later to be transformed with the construction of a spacious aula with mosaic floor, already likely to have been used for Christian worship during this phase, subdivided into three naves by two rows of eight columns.